Given the immense cultural and ecological value of forests, the US federal government, Tribal Nations, and the public sector are considering strategies for sustaining forests, including a recent Executive Order by President Biden and the proposed National Old Growth Amendment. In this joint presentation, Cristina Eisenberg and Susan J. Prichard synthesize the best-available Western Science and braid it together with Indigenous Knowledge (IK), called Two-Eyed Seeing, to consider the historical, pre-settlement context of old and mature forests, as well as forward-looking strategies for climate change adaptation. A cross-boundary issue for many forests is a legacy of settler colonialism and loss of Indigenous stewardship and beneficial fire, including cultural burning. Informed by the geographic diversity of forests and communities that live within them, Eisenberg and Prichard provide a brief overview of ecocultural systems and climate adaptation strategies across major forested regions of North America, and an overview of the strategies we recommend for stewarding these forested regions for climate resilience, and the principles for partnering ethically with Tribal Nations in forest ecocultural restoration.